Research · 研究方向
We explore the chemistry that biology has not yet evolved—using enzyme active sites as programmable environments for radical reactions and precision carbohydrate synthesis.
探索自然界尚未进化出的催化功能，发展可编程的酶促非天然反应。
酶促非天然反应
We reprogram enzyme scaffolds for new-to-nature reactivity by coupling light- and electricity-enabled radical generation with active-site control, enabling bond formation with high chemo- and stereoselectivity.
糖类物质精准合成
We develop catalytic routes to architecturally diverse C- and N-glycosides, with particular emphasis on programmable glycosyl-radical precursors, modular coupling partners and anomerically defined products.
可持续合成与生物制造
We translate enabling reactions into integrated enzymatic cascades, linking engineered catalysts with biosynthetic modules to deliver complex, high-value carbohydrate molecules through concise and resource-efficient routes.
